In the presence of L-glutamate, the pyruvate is transformed into L-alanine in a reaction catalysed by glutamate pyruvate transaminase (GPT):(1) L-lactate + NAD+ pyruvate + NADH + H+(2) D-lactate + NAD+ pyruvate + NADH + H+(3) Pyruvate + L-glutamate L-alanine + a-ketoglutarate
En présence de L-glutamate, le pyruvate est transformé en L-alanine, réaction catalysée par la glutamate-pyruvate-transaminase (GPT)(1) L-lactate + NAD+ pyruvate + NADH + H+(2) D-lactate + NAD+ pyruvate + NADH + H+(3) Pyruvate + L-glutamate L-alanine + a cétoglutarate