Traduction de «cessation d’un accord de codéveloppement » (Français → Néerlandais) :

Comparée à la marge opérationnelle core qui a progressé de 1,8 point de pourcentage, la marge opérationnelle a reflété les charges d’intégration liées à l’acquisition d’EBEWE Pharma, des charges uniques pour la cessation d’un accord de codéveloppement et des provisions pour des règlements juridiques.
The operating income margin increase in the first nine months as compared to the growth in core operating income margin of 1.8 percentage points reflected the acquisition-related charges for the integration of EBEWE Pharma, one-time charges for the termination of a co-development agreement and provisions for legal settlements.

La réduction de la marge opérationnelle, qui contraste avec l'augmentation de la marge opérationnelle core, reflète les charges d'intégration d'EBEWE Pharma après son acquisition, des charges uniques pour la cessation d'un accord de codéveloppement et des provisions pour règlements juridiques.
The reduction of the operating margin in the period as compared to the growth in core operating margin reflected the acquisition-related charges for the EBEWE Pharma integration, one-time charges for the termination of a codevelopment agreement and provisions for legal settlements.

Alors que la marge opérationnelle core s’est améliorée de 1,1 point de pourcentage, l’amélioration plus faible de la marge opérationnelle est due à des charges uniques liées à la cessation d'un accord de codéveloppement et à la comptabilisation du prix d'achat d'EBEWE Pharma.
The lower improvement of the operating margin as compared to the core operating margin increase of 1.1 percentage points reflected one-time charges related to the termination of a co-development agreement and purchase price accounting for EBEWE Pharma.

Les principaux facteurs de cette réduction sont des charges liées à l’intégration d’EBEWE Pharma (–0,7 point de pourcentage), des coûts exceptionnels pour la cessation d’un accord de codéveloppement (–0.8 point) et des provisions pour le règlement du litige concernant le prix de gros moyen aux Etats-Unis (–1.9 point).
Key factors for the reduction included acquisitionrelated charges for the EBEWE Pharma integration (–0.7 percentage points), exceptional costs for termination of a co-development agreement (–0.8 percentage points) and provisions for settlement of Average Wholesale Pricing litigation in the US (–1.9 percentage points).

Eléments exceptionnels: Recherche et développement inclut une charge pour la cessation d’un contrat de codéveloppement; Autres charges représente une charge d’USD 38 millions pour un règlement juridique aux Etats-Unis
Exceptional items: Research & Development includes an expense for termination of a co-development contract; Other expense represents a USD 38 million charge for a legal settlement in the US.

Eléments exceptionnels: Recherche et développement comprend une charge pour la cessation d’un contrat de codéveloppement
Exceptional items: R&D includes an expense for termination of a co-development contract.

Eléments exceptionnels: Recherche et développement comprend une charge pour la cessation d’un contrat de codéveloppement; Autres produits comprend principalement un gain lié à des modifications de la comptabilisation de régimes de retraites d’USD 265 millions et un gain de cession d’USD 33 millions pour Tofranil dans Pharmaceuticals; Autres charges comprend USD 152,5 millions pour le règlement provisoire d’un cas de discrimination sexuelle aux USA dans Pharmaceuticals, USD 45 millions pour un règlement juridique dans Vaccins et Diagnostic, une charge de restructuration d’USD 26 millions aux USA dans Pharmaceuticals ainsi qu’une provision d’USD 25,5 millions liée à une enquêtre gouvernementale aux USA dans Pharmaceuticals.
Exceptional items: R&D includes an expense for termination of a co-development contract; Other income includes mainly a Swiss pension curtailment gain of USD 265 million in Corporate and a divestment gain of USD 33 million for Tofranil in Pharmaceuticals; Other expense includes a USD 152.5 million provision for a gender discrimination case in the US in Pharmaceuticals, USD 45 million for a legal settlement in Vaccines and Diagnostics, a USD 26 million charge for restructuring in the US in Pharmaceuticals as well as a USD 25.5 million provision in connection with a government investigation in the US in Pharmaceuticals.

Spontaneous cessation rate: 2.5% OR counselling only: 1.73 Incremental OR NRT gum (relative to counselling only): 1.63 Incremental OR NRT patch (relative to counselling only): 1.79 Incremental OR NRT spray (relative to counselling only): 2.35 Incremental OR NRT inhaler (relative to counselling only): 2.14 Incremental OR Buproprion (relative to counselling only): 2.30 % of smokers still under treatment after the first month: 50% (range 40-60% in sensitivity analysis) % of smokers still under treatment after the second month: 20% (range 15-25% in sensitivity analysis) Lifetime relapse probability after one year of abstinence: 35% (range 10-50% in sensitivity analysis) Effect of smoking cessation on mortality derived from the results of the American Cancer Society Prevention Study II. The mortality rate for former smokers was projected by calculating a weighted average of the incremental differentials between mortality rates of neversmokers and smokers, weighted according to the duration of abstinence.
Spontaneous cessation rate: 2.5% OR counselling only: 1.73 Incremental OR NRT gum (relative to counselling only): 1.63 Incremental OR NRT patch (relative to counselling only): 1.79 Incremental OR NRT spray (relative to counselling only): 2.35 Incremental OR NRT inhaler (relative to counselling only): 2.14 Incremental OR bupropion (relative to counselling only): 2.30 % of smokers still under treatment after the first month: 50% (range 40-60% in sensitivity analysis) % of smokers still under treatment after the second month: 20% (range 15-25% in sensitivity analysis) Lifetime relapse probability after one year of abstinence: 35% (range 10-50% in sensitivity analysis) Effect of smoking cessation on mortality derived from the results of the American Cancer Society Prevention Study II. The mortality rate for former smokers was projected by calculating a weighted average of the incremental differentials between mortality rates of neversmokers and smokers, weighted according to the duration of abstinence.