Vertaling van "fibrillation and of antiplatelet therapy in patients " (Frans → Nederlands) :

For primary prevention of stroke, adequate blood pressure reduction, and treatment of hyperlipidemia, use of antithrombotic therapy in patients with atrial fibrillation and of antiplatelet therapy in patients with myocardial infarction are effective and supported by evidence from several
For primary prevention of stroke, adequate blood pressure reduction, and treatment of hyperlipidemia, use of antithrombotic therapy in patients with atrial fibrillation and of antiplatelet therapy in patients with myocardial infarction are effective and supported by evidence from several randomized trials.1 Effective strategies for the secondary prevention of stroke include

randomized trials.1 Effective strategies for the secondary prevention of stroke include treatment of hypertension and hyperlipidemia, antithrombotic therapy for patients with atrial fibrillation, and antiplatelet therapy (Evidence level 1). 1 Statins are effective in the prevention of stroke, although evidence remains limited to heart disease patients (Evidence level 1). 2, 3
treatment of hypertension and hyperlipidemia, antithrombotic therapy for patients with atrial fibrillation, and antiplatelet therapy (Evidence level 1).1 Statins are effective in the prevention of stroke, although evidence remains limited to heart disease patients (Evidence level 1).2, 3

Search Date February 2009. [http ...]
Aguilar MI, Hart R. Antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks.

Hart RG, Pearce LA et Aguilar MI: Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.
Hart RG, Pearce LA en Aguilar MI: Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation.

La démonstration de l'efficacité clinique du dabigatran etexilate est issue de l'étude RE-LY (Randomized Evaluation of Long-term anticoagulant therapy), une étude multicentrique, internationale, randomisée en groupes parallèles, évaluant deux doses administrées en aveugle de dabigatran etexilate (110 mg et 150 mg deux fois par jour) par rapport à l'administration en ouvert de warfarine chez des patients présentant une fibrillation atriale et à risque modéré à élevé d’AVC et d’ES.
Het klinisch bewijs voor de werkzaamheid van dabigatran etexilaat is afkomstig uit het RE-LY-onderzoek (Randomized Evaluation of Long-term anticoagulant therapY), een multi-center multinationaal gerandomiseerde studie met parallelle groepen met twee geblindeerde doseringen van dabigatran etexilaat (110 mg en 150 mg tweemaal per dag) vergeleken met open-label warfarine bij patiënten met atriumfibrilleren met een matig tot hoog risico op CVA en systemische embolie.

Hylek EM, Evans-Molina C, Shea C, Henault LE et Regan S: Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation.
Hylek EM, Evans-Molina C, Shea C, Henault LE en Regan S: Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation.