Remming van de hormoonproductie kan worden veroorzaakt door directe competitieve binding aan een enzym in de pathway, impact op cofactoren zoals NADPH (Nicotinamide Adenine Dinucleotide Phosphate) en cAMP (cyclic Adenosine Monophosphate), en/of verhoging van het steroïdmetabolisme of onderdrukking van de genexpressie van bepaalde enzymen in de steroïdogenese-pathway.
Inhibition of hormone production can be due to direct competitive binding to an enzyme in the pathway, impact on co-factors such as NADPH (Nicotinamide Adenine Dinucleotide Phosphate) and cAMP (cyclic Adenosine Monophosphate), and/or increase in steroid metabolism or suppression of gene expression of certain enzymes in the steroidogenesis pathway.
